Underlying causes of unexplained infertility

Unexplained Infertility: The Underlying Causes

Unexplained Infertility, Explained.

Common “explained” causes of infertility are hormone imbalance/irregular cycles, endometriosis, PCOS, premature ovarian failure, high prolactin, blocked fallopian tubes, fibroids… but what happens when you don’t have any of these and you are labeled with “unexplained infertility”?

The human reproductive system is an extremely delicate system that is easily influenced by emotions, inflammation, food sensitivities, toxins, mold, heavy metals, and hidden infections. 

Learn how each of these things can affect you and your partner’s fertility.


Blood Sugar

Blood sugar, specifically glucose, plays an essential role in fertility because it provides the necessary energy for reproductive processes. Imbalanced blood sugar can easily throw all the necessary sex hormones out of balance.


Gut & Liver Health

A healthy GI tract and liver, free of inflammation and pathogens is imperative for absorbing nutrients from our food. The whole GI system is also an important center for hormone production, metabolism and detoxification.


Hidden Infections

Hidden or stealth infections can be in the form of pathogenic bacteria and parasites. They impact fertility by causing inflammation, disrupting hormonal balance, and impairing reproductive processes.



Mitochondria play a crucial role in fertility because they are responsible for producing energy in the form of adenosine triphosphate (ATP), which is essential for the various processes involved in reproduction.


Toxin Load

Toxins can have a negative impact on fertility by interfering with hormone balance, creating inflammation and oxidative stress that damages reproductive tissues, egg quality and sperm quality.



The thyroid is a delicate gland that is important for fertility because it plays a crucial role in regulating hormones that are vital for reproductive processes. Several thyroid markers need to be checked and cross-referenced in order to be sure the thyroid is functioning optimally.


Food sensitivities

Food sensitivities can be a by product of an inflamed, leaky gut. If food molecules are able to break through the intestinal wall and enter the blood stream, there will likely be an immune response which will cause chronic inflammation that can throw hormones out of balance and damage reproductive tissues.



Mental and emotional health play a significant role in fertility because the mind and body are interconnected, and psychological well-being can impact reproductive health.

If you are dealing with unexplained infertility and would like help figuring out what your underlying cause is, please book a Discovery Call with me to learn how I can help you.

Picture of Shannon South, FNTP

Shannon South, FNTP

Shannon South is a Functional Nutritional Therapy Practitioner specializing in fertility and hormones. She gave birth to her one and only child at age 43, after a long struggle with infertility. She and her beautiful family live in Brooklyn, NY.

Free resources

Optimizing fertility with nutrition
Download my Ultimate guide to Fertility Nutrition.
Fertility and the mitochondria
Take the Mitochondria Mastery quiz.
Fertility Supportive Modalities
Download my Top 11 Fertility Supportive Modalities Guide.